DNA encoding procine interleukin-10

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 4352523, 4353651, 435325, 536 235, C12N 510, C12N 1524

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056248237

ABSTRACT:
Purified DNA encoding porcine IL-10, porcine IL-10, and methods of inducing immunological tolerance and inhibiting graft versus host disease.

REFERENCES:
patent: 5231012 (1993-07-01), Mosmann et al.
Haynes et al., (1989) "The Role of Leukocyte Adhesion Molecules in Cellular Interactions: Implications for the Pathogenesis of Inflammatory Synovitis"; vol. 11, pp. 163-185.
Fischel, et al., (1991) "Prolonged Survival of a Discordant Cardiac Xenograft in a Rhesus Monkey," Transplantation Proceedings, vol. 23, No. 1, pp. 589-590, Feb. 1991.
Sachs, et al. "Human Immunology of Xenogaft Rejection" Human Immunology; vol. 28, pp. 245-251; 1990.
Wee, et al, (1992) "The Effects of OKT4A Monoclonal Antibody on Cellular Immunity of nonhuman primate renal allografts recipients" Transplantations, vol. 53, pp. 501-507, Mar. 1992.
Reeck et al. 1987. Cell 50:667.
Lewin. 1987 Science 237:1570.
Bowie et al. 1990. Science 247:1306-1310.
Abramowicz et al., "Neonatal Induction of Transplantation Tolerance in Mice is Associated With In Vivo Expression of IL-4 and -10 mRNAs" Transplantation Proceedings, vol. 25, No. 1, pp. 312-313, Feb. 1993.
Takeuchi et al., "Heart Allografts In Murine Systems. The Differential Activation of Th2-like Effector Cells in Peripheral Tolerance" Transplantation, vol. 53, No. 6, pp. 1281-1294, Jun. 1992.
Merville et al., "Detection of Single Cells Secreting IFN-Gamma, IL-6, and IL-10 in Irreversible Rejected Human Kidney Allografts, and Their Modulation by IL-2 and IL-4" Transplantation, vol. 55, No. 3, pp. 639-646, Mar. 1993.
Moore et al., "Interleukin-10" Annu. Rev. Immunol., vol. 11, pp. 165-190, 1993.
Howard et al., "Interleukin 10 Protects Mice from Lethal Endotoxemia" J. Exp. Med., vol. 177, pp. 1205-1208, Apr. 1993.
Ishida et al., "Continuous Anti-Interleukin 10 Antibody Administration Depletes Mice of Ly-1 B Cells but Not Conventional B Cells" J. Exp. Med., vol. 175, pp. 1213-1220, May 1992.
Hsieh et al., "Development of T.sub.H 1 CD4.sup.+ T Cells Through IL-12 Produced by Listeria-Induced Macrophages" Science, vol. 260, pp. 547-549, Apr. 23, 1993.
Macatonia et al., "Dendritic cells and macrophages are required for Th1 development of CD4.sup.+ T Cells from .alpha..beta. TCR transgenic mice: IL-12 substitution for macrophages to simulate IFN-.gamma.Production is IFN.gamma.-dependent" International Immunology, vol. 5, No. 9, pp. 1119-1128. 1993.
Macatonia et al., "Differential Effect of IL-10 on Dendritic Cell-Induced T Cell Proliferation and IFN-.gamma. Production" The Journal of Immunology, vol. 150, No. 9, pp. 3755-3765, May 1, 1993.
Fiorentino et al., "IL-10 Inhibits Cytokine Production by Activated Macrophages" The Journal of Immunology, vol. 147, No. 11, pp. 3815-3822, Dec. 1, 1991.
Fiorentino et al., "Two Types of Mouse T Helper Cell. IV. Th2 Clones Secrete a Factor that Inhibits Cytokine Production by Th1 Clones" J. Exp. Med., vol. 170, pp. 2081-2095, Dec. 1989.
Moore et al., "Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI" Science, vol. 248, pp. 1230-1234, Jun. 8, 1990.
Viera et al., "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: Homology to Epstein-Barr virus open reading frame BCRFI" Proceedings of the National Acadamy of Sciences, vol. 88, pp. 1172-1176, Feb. 1991.
Fernandez-Botran et al., "Lymphokine-mediated Regulation of the Proliferative Response of Clones of T Helper 1 and T Helper 2 Cells" J. Exp. Med., vol. 168, pp. 543-558, Aug. 1988.
Fiorentino et al., "IL-10 Acts on the Antigen-presenting Cell to Inhibit Cytokine Production by Th1 Cells" The Journal of Immunology, vol. 146, No. 10, pp. 3444-3451, May 1991.
Howard et al., "Biological properties of interleukin 10" Immunology Today, vol. 13, No. 6, pp. 198-200, 1992.
Feng et al., "Molecular Cloning of Rat Cytokine Synthesis Inhibitory Factor (IL-10) cDNA and Expression in Spleen and Macrophages" Biochemical and Biophysical Research Communications, vol. 192, No. 2, pp. 452-458, Apr. 30, 1993.
De Waal Malefyt et al., "Interleukin 10(IL-10) Inhibits Cytokine Synthesis by Human Monocytes: An Autoregulatory Role of IL-10 Produced by Monocytes" J. Exp. Med., vol. 174, pp. 1209-1220, Nov. 1991.
Cherwinski et al., "Two Types of Mouse Helper T Cell Clone. III. Further Differences in Lymphokine Synthesis between Th1 and Th2 Clones Revealed by RNA Hybridization, Functionally Monospecific Bioassays, and Monoclonal Antibodies" J. Exp. Med., vol. 166, pp. 1229-1244, Nov. 1987.
Horowitz et al., "Autocrine growth inhibition of a cloned line of helper T cells" Proceedings of the National Academy of Sciences, vol. 83, pp. 1886-1890, Mar. 1986.
Mosmann et al., "Two Types of Murine Helper T Cell Clone I. Definition According to Profiles of Lymphokine Activities and Secreted Proteins" The Journal of Immunology, vol. 136, No. 7, pp. 2348-2357, Apr. 1, 1986.
Gajewski et al., "Anti-proliferative Effect of IFN-.gamma.in Immune Regulation. I. IFN-.gamma.Inhibits the Proliferation of Th2 but Not Th1 Murine Helper T Lymphocyte Clone" The Journal of Immunology, vol. 140, No. 12, pp. 4245-4252, Jun. 15, 1988.
Del Prete et al., "Human IL-10 is Produced by Both Type 1 Helper (Th1) and Type 2 Helper (Th2) T Cell Clones and Inhibits Their Antigen-Specific Proliferation and Cytokine Production" The Journal of Immunology, vol. 150, No. 2, pp. 353-360, Jan. 15, 1993.
O'Garra et al., "Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10" vol. 2, No. 9, pp. 821-832, 1990.

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