Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1994-07-07
1995-08-08
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
536 2431, 536 2351, 4353201, 4352542, 4352351, 4352523, C12N 121, C12N 1516
Patent
active
054398215
ABSTRACT:
The subject invention concerns novel peptides which have the property of interfering with the biosynthesis of the enzyme trypsin. This property enables the use of these peptides to, for example, inhibit the formation of progeny in blood-ingesting insects, since trypsin is an essential enzyme for food digestion which provides the essential building blocks for egg development in such insects.
REFERENCES:
patent: 5011909 (1991-04-01), Borovsky et al.
patent: 5130253 (1992-07-01), Borovsky et al.
Borovsky, Dov (1985) "Isolation and Characterization of Highly Purified Mosquito Oostatic Hormone" Archives of Insect Biochemistry and Physiology 2:333-349.
Borovksy, Dov (1988) "Oostatic Hormone Inhibits Biosynthesis of Midgut Proteplytic Enzymes and Egg Development in Mosquitos" Archives of Insect Biochemistry and Physiology 7:187-210.
Borovsky, D. et al. (1990) "Mosquito oostatic factor: a novel decapeptide modulating trypsin-like enzyme biosynthesis in the midgut" FASEB J. 4:3015-3020.
Rayne, R. C., M. O'Shea (1992) "Inactivation of Neuropeptide Hormones (AKH I and AKH II) Studied In Vivo and In Vitro" Insect Biochem. Molec. Biol. 22(1):25-34.
Schwartz, J.-C. et al. (1981) "Biological Inactivation of Enkephalins and the Role of Enkephalin-Dipeptidyl-Carboxypeptidase Enkephalinase) as Neuropeptidase" Life Sciences 29:1715-1740.
Charbonneau, Harry (1989) "Strategies for Obtaining Partial Amino Acid Sequence Data from Small Quantities (<5 nmol) of Pure or Partially Purified Protein" A Practical Guide to Protein and Peptide Purification for Microsequencing pp. 15-30.
Sober, H. A. (1968) "Handbook of Biochemistry" The Chemical Rubber Co., Cleveland, Ohio, p. C70.
Borovsky Dov
Carlson David A.
Schmickel David
Schwartz Richard A.
The United States of America as represented by the United States
University of Florida Research Foundation
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