Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1991-07-15
1993-05-11
Hill, Jr., Robert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352401, 4353201, 435255, 4352523, 536 231, 536 235, 514 12, C12N 1512, C12N 121, C12P 2102
Patent
active
052100278
ABSTRACT:
This invention provides a purified polypeptide useful as an antimicrobial agent. This purified polypeptide has been derived from human granulocytes, and has a molecular weight of about 3,700 daltons and the N-terminal amino acid sequence val-cys-ser-cys-arg-leu-val-phe-cys-arg-arg-thr-glu-leu-arg-val-gly-asn-cy s-leu-ilu-gly-gly-val-ser-phe-thr-tyr-cys-cys-thr-arg-val. This invention also provides methods for producing this polypeptide, pharmaceutical compositions containing the polypeptide, and uses thereof.
REFERENCES:
patent: 4705777 (1987-11-01), Lehrer et al.
Griffith Joseph E.
Marra Marian N.
Scott Randal W.
Wilde Craig G.
Hill Jr. Robert J.
Incyte Pharmaceuticals Inc.
Ossanna Nina
White John P.
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