DNA encoding neurotrophic growth factors

Details DNA encoding neurotrophic growth factors DNA encoding neurotrophic growth factors

1993-03-22

1996-04-02

Draper, Garnette D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

435 691, 4352401, 4353201, 935 23, 935 66, C07H 2104, C12N 1512, C12N 1511, C12N 1500

Patent

active

055041973

ABSTRACT:
Neurotrophic growth factor proteins isolated from novel clonal cell lines grown in culture are mitogenic for fibroblasts and glial cells; some promote nerve cell survival and are prospectively useful in treating diseases such as Parkinson's and Alzheimer's which result in cell death in the nervous system, as well as in treating patients prone to epileptic seizures and patients suffering from trauma to the CNS. Certain of these proteins may be useful in nerve regeneration as well as in treating such diseases and injuries. Some are particularly useful in promoting lung development. These proteins are also useful in methods of treating a patient to promote nerve cell regeneration in degenerative eye diseases. The proteins can be topically applied in suitable compositions for wound-healing applications, and they can be administered parenterally to promote lung development and to treat patients afflicted with nerve damage and/or nerve disease.

REFERENCES:
patent: 5202428 (1993-04-01), Schubert
Barinyage Science 264:772-774 (1994).
Bowie et al. Science 247: 1306-10 (1990).
Burgess et al. Ann Review Biochem 58:575-606 (1989).
Berg Ann Rev Neurosci 7:149-170 (1984).
Watters, et al. J. of Neurochem 49(3):705-13 (1987).
Wagner, J of Neuroscience 6(1):61-67 (1986).
Heymanns et al. Proc. Natl Acad Sci 84:7758-62 (1987).

Affiliated with

Also associated with

Rating

DNA encoding neurotrophic growth factors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA encoding neurotrophic growth factors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA encoding neurotrophic growth factors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2017274