DNA encoding murine interleukin-5 receptor

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 691, 4352523, 4353201, 435361, 435365, C12N 1524, C12P 2100, C07H 2107

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057602042

ABSTRACT:
The invention provides an isolated cDNA sequence coding for murine interleukin 5 receptor, murine secretory interleukin 5 receptor, human interleukin 5 receptor, and human secretory interleukin 5 receptor and products including murine interleukin 5 receptor, murine secretory interleukin 5 receptor, and human interleukin 5 receptor which are produced using the isolated cDNA sequence. These products may be useful for a therapeutic agent for autoimmune disorders and diseases with eosinophilia in which human IL-5 is believed to be involved.

REFERENCES:
patent: 4859609 (1989-08-01), Dull et al.
patent: 5006459 (1991-04-01), Kung et al.
Takaki et al., 1991, Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor, The Embo Journal 10(10):2833-2838.
Migita et al., Cell. Immunol 133, 1991, pp. 484-497.
Hitoshi, et al., 1989, "Interferon-gamma inhibits the proliferation but not the differentiation of murine B cells in response to IL-5", Int. Immunol., 1(2):185-90.
Hitoshi et al., 1990, "Distribution of IL-5 receptor-positive B cells", J. of Immunol., 144:4218-25.
Kinashi et al., 1986, "Cloning of complementary DNA encoding T-cell replacing factor and identify with B-cell growth factor II", Nature, 324(6092):70-73.
Matsumoto et al., 1989, Interleukin-5 induces maturation but not class switching of surface Iga-positive B cells into IgA-secreting cells, Immunology, 66:32-38.
Migita et al., 1991, "Characterization of the human IL-5 receptors on eosinophils", Cell. Immunol., 166:484-97.
Mita et al., 1988, "Receptors for T cell-replacing factor/interleukin 5", J. Exp. Med., 168:863-78.
Mita et al., 1989, "Rapid methods for purification of human recombinant interleukin-5 (IL-5) using the anti-murine IL-5 antibody-coupled immunoaffinity column", J. Immunol. Methods, 125:233-41.
Mita et al., 1989, "Characterization of high-affinity receptors for interleukin 5 on interleukin 5-independent cell lines", Proc. Natl. Acad. sci. USA 86:2311-15.
Murata et al., 1990, "Interleukin 5 and interleukin 3 induce serine and tyrosine phosphorylations of several cellular proteins in an interleukin 5-dependent cell line", Biochem. and Biophys. Res. Comm., 173(3):1102-08.
Sanderson et al., 1988, "Molecular and cellular biology of eosinophil diferentiation factor (interleukin-5) and its effects on human and mouse B cells", Immunological Reviews, 102:29-50.
Sonoda et al., 1989, "Transforming growth factor .beta. induces Iga production and acts additively with interleukin 5 for IgA production", J. Exp. Med., 170:1415-20.
Spry, Christopher J.F., 1988, Eosinophils: a comprehensive review, and guide to the scientific and medical literature, Oxford University Press, 262-287.
Takaki et al., 1990, "Molecular cloning and expression of the murine interleukin-5 receptor", EMBO Journal, 9(13):4367-74.
Takatsu et al., 1988, "T cell-replacing factor (TRF)/interleukin 5 (IL-5); molecular and functional properties", Immunological Reviews, 102:107-135.
Takatsu and Tominaga, 1990, "Interleukin 5 as a hematopoietic cell growth and differentiation factor", Growth Factors, Differentiation Factors, and Cytokines, A. Habenicht (ed.), 147-62.
Tominaga et al., 1988, "Molecular properties and regulation of mRNA expression for murine T cell-replacing factor/IL-5", J. Immunol., 140(4):1175-81.
Tominaga et al., 1989, "Establishment of IL-5 dependent early B cell lines by long-term bone marrow cultures", Growth Factors, 1:135-46.
Tominaga et al., 1990, "Role of carbohydrate of moiety of IL-5", J. Immunol., 144(4):1345-52.
Yamaguchi et al., 1989, "Mechanisms of the interleukin 5-induced differentiation of B cells", 106(5):837-843.
Yamaguchi et al., 1990, "Characterization of the murine interleukin 4 receptor by using a monoclonal antibody", Int. Immunol., 2(2):181-187.
Mita al., Pnas 86, pp. 2311-2315 (1989).
Devos et al., Embo 10(8) 1991, pp. 2133-2137.
Devos et al., Biochem. Biophys. Res. Comm. 172(2) p. 570-575 (1990).
Kaczmerski et al., Blood Res. 5(3) pp. 193-203 (1991).
Tavernier et al., Pnas 89 pp. 7041-7045 (1992).
Hitoshi et al., J. Immunol., 144 pp. 4218-4225 (1990).
Cosman, DNA and Protein Engineering Techniques vol. 2(1) pp. 1-3 (1990).
Dower et al., J. Clin. Immunol. 10(6) pp. 289-299 (1990).
Bazan, Immunol. Today 11(10) pp. 350-354 (1990).
Takaki et al., Lymphokine Research 9:572, 1990.
Gearing et al., Embo Journal 8:3667-3676, 1989.
Yamaguchi et al., International Immuno. 2:181-188, 1990.
Rolink et al., J.Exp. Med. 169:1693-1701, 1989.
Takaki et al., "Embo Journal "9:4367-4374, 1990.
Tavernier et al., Cell 66 1175-1184, 1991.

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