Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1989-10-20
1992-04-07
Schwartz, Richard A.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435214, 435183, 935 10, C12N 1515
Patent
active
051029952
ABSTRACT:
A modified heparin cofactor II is disclosed, HCII (Leu.sub.444 .fwdarw.Arg), which has substantially improved inhibitory activity against thrombin compared to native HCII or antithrombin.
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Blinder Morey A.
Derechin Vivianna M.
Tollefsen Douglas M.
LeGuyader John L.
Meyer Scott J.
Schwartz Richard A.
Washington University
Williams, Jr. James W.
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