DNA encoding mammalian neuropeptide FF (NPFF) receptors and...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C435S069100, C435S320100, C435S325000, C530S350000

Reexamination Certificate

active

06849727

ABSTRACT:
This invention provides isolated nucleic acids encoding mammalian NPFF receptors, purified mammalian NPFF receptors, vectors comprising nucleic acid encoding mammalian NPFF receptors, cells comprising such vectors, antibodies directed to mammalian NPFF receptors, nucleic acid probes useful for detecting nucleic acid encoding mammalian NPFF receptors, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding mammalian NPFF receptors, transgenic, nonhuman animals which express DNA encoding normal or mutant mammalian NPFF receptors, methods of isolating mammalian NPFF receptors, methods of treating an abnormality that is linked to the activity of the mammalian NPFF receptors, as well as methods of determining binding of compounds to mammalian NPFF receptors, methods of identifying agonists and antagonists of NPFF receptors, and agonists and antagonists so identified.

REFERENCES:
patent: 0884387 (1998-12-01), None
patent: 0000606 (2000-01-01), None
patent: 0029441 (2000-05-01), None
patent: 0031107 (2000-06-01), None
Lukacs GL et al., The cystic fibrosis transmembrane regulator is present and functional in endosomes. Role as a determinant o endosomal pH.J Biol Chem. Jul. 25, 1992;267(21):14568-14572.*
Voet et al. Biochemistry. 1990. John Wiley & Sons, Inc. pp. 126-128 and 228-234.*
Mickle JE et al. Genotype-phenotype relationships in cystic fibrosis. Med Clin North Am. May 2000;84(3):597-607.*
Expressed Sequence Tags Database Accession No. AA 449919, published Jun. 4, 1997.
Expressed Sequence Tags Database Accession No. AA 449920, published Jun. 4, 1997.
Allard, et al., “Mechanisms Underlying the Cardiovascular Responses to Peripheral Administration of NPFF in the Rat”,J. Pharmacol. Exp. Ther. 274(1): 577-583 (Jul. 1995).
Ciko{hacek over (s)}, et al., “Sequence and Tissue Distribution of a Novel G-Protein-Coupled Receptor Expressed Prominently in Human Placenta,”Biochem. and Biophysical Res. Comm.,Mar. 16, 1999, 256: 352-356.
Devillers, et al., “Characterization of a Potent Agonist for NPFF Receptors: Binding Study on Rat Spinal Cord Membranes”Neuropharmacology 33(5): 661-669 (May 1994).
Dupouy, et al., “Species Differences in the Localization of Neuropeptide FF Receptors in Rodent and Lagomorph Brain and Spinal Cord”Peptides 17(3): 399-405 (1996).
Knapp, et al., “Molecular Biology and Pharmacology of Cloned Opioid Receptors”FASEB J. 9(7): 516-525 (Apr. 1995).
Payza, et al., “Modulation of Neuropeptide FF Receptors by Guanine Nucleotides and Cations in Membranes of Rat Brain and Spinal Cord”J. Neurochem. 60(5): 1894-1899 (May 1993).

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