DNA encoding (Lys.sup.46, Asp.sup.97, Asp.sup.113) and (Lys.sup.

Details DNA encoding (Lys.sup.46, Asp.sup.97, Asp.sup.113) and (Lys.sup. DNA encoding (Lys.sup.46, Asp.sup.97, Asp.sup.113) and (Lys.sup.

1989-09-14

1993-06-22

Martinell, James

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 691, 4351723, 435243, 435256, 4353201, 536 236, 935 10, C12P 2100, C12N 1500, C12N 1529, C12N 1570, C12N 1581

Patent

active

052216241

ABSTRACT:
Genes are disclosed which are capable of directing the synthesis in a selected host microorganism of thaumatin I polypeptides having improved taste characteristics characterized by having the amino acid sequence of natural thaumatin I including a lysine amino acid residue substituted for asparagine in the 46th position from the amino terminal end, an aspartate amino acid residue substituted for asparagine in the 113th position from the amino terminal end and an aspartate amino acid residue substituted for lysine at either the 97th or 137th residue from the amino terminal end.

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