DNA encoding lymphocyte chemoattractant factor (LCF) and uses th

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 691, 4351723, 4352401, 4352402, 4352523, 43525233, 43525411, 435325, 536 231, 536 235, C12N 1519, C12N 2100

Patent

active

058077120

ABSTRACT:
Purified DNA encoding lyphocyte chemoattractant factor (LCF) and the recombinant proteins expressed from such DNA are disclosed. In addition, the invention provides methods for suppressing an LCF-CD4 interaction and screening candidate LCF agonists or antagonists. The invention also provides compositions and methods useful for stimulating proliferation of CD4+ T-cells in a mammal.

REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
Center, et al. (Feb. 1995) "The Lymphocyte Chemoattractant Factor", J. Lab. Clin. Med. 125(2):167-172.
Cruikshank, et al. (May 24, 1994) "Molecular and Functional Analysis of a Lymphocyte Chemoattractant Factor: Association of Biologic Function with CD4 Expression", Proc. Natl. Acad. Sci. USA 91(11):5109-5113.
(May 1996) Standing Committee on Interleukin Designation "Terminology Note: Interleukin 16 (IL-16)", Eur. J. Immunol. 26(5)1196.
Rand et al. J. Exp. Med vol. 173 pp. 1521-1528 (1991).
Smith et al. Proc. Natl. Acad. Sci (USA) vol. 82 pp. 8404-8408 (1985).
Berman et al., Cellular Immunology 95:105-112 (1985).
Berman et al., AM Rev. Respir. Dis. 142:238-257 (1990).
Cambell, "Monoclonal Antibody Technology, The Production and Characterization of Rodent and Human Hybidomas", Elservier Science Publishers (Amsterdam), pp. 1-4 and 29 (1984).
Center et al., The Journal of Immunology 128:2563-2568 (1982).
Cruikshank et al., The Journal of Immunology, 138:3817-3823 (1987).
Cruikshank et al., The Journal of Immunology, 146:2928-2934 (1991).
Cruikshank et al., EMBL Database, Accession No. M90391 (1992).
Cruikshank et al., The Journal of Immunology 128:2569-2574 (1982).
Rand et al., J. Exp. Med 173:1521-1528 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DNA encoding lymphocyte chemoattractant factor (LCF) and uses th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA encoding lymphocyte chemoattractant factor (LCF) and uses th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA encoding lymphocyte chemoattractant factor (LCF) and uses th will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-85958

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.