DNA encoding interleukin IL-1.beta. mutant

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 711, 435 712, 435 6952, 4351723, 4352523, 4353201, 935 11, 935 22, 935 66, 935 72, 530351, C12N 1524, C12N 510

Patent

active

058470980

ABSTRACT:
A homogeneous interleukin 1.beta. (IL-1.beta.), its derivative having a modified amino acid sequence of IL-1.beta., a gene coding for said derivative, medical composition comprising said derivative as a pharmaceutically effective component and a medicinal use of homogeneous IL-1.beta. and the derivative.

REFERENCES:
patent: 4518584 (1985-05-01), Mark et al.
patent: 4568640 (1986-02-01), Rubin
patent: 4762914 (1988-08-01), Auron et al.
patent: 4766069 (1988-08-01), Auron et al.
patent: 4959314 (1990-09-01), Mark et al.
Zoller et al, Nucleic Acid Res., 10(20):6487-6500 (1982).
Clark et al, Nucleic Acid Res., 14920):7897-7914 (1986).
Tsuji et al, Biochem., 26:3129-3134 (1987).
Wang et al, Science, 224:1431-1443 (1984).
Wells et al, Gene, 34:315-323 (1985).
Suhamanian, Bio/Technol, 3:597 (1985).
Von Heijne, Eur. J. Biochem., 133:17-21 (1983).
Perlman et al, J. Mol. Biol., 167:391-409 (1983).
Inouge et al, Protein Engineering, Ed., pp 157-171 (1986).
Robinson et al, introduction to Proteins and Protein Engineering, pp. 258-259 (1986).
Regenmortel, TIBS, 11:36-39 (1986).
Darrel et al, Nature, 283:433 (1980).
March et al, Nature, 315(6021):641-647 (1985).
Dinarello, Reviews of Infections Diseases, 691):51-95 (1984).
J. of Immunology, 122(5):2112-2118 (1979).
Federation Proceedings, 41(2):257-262 (1982).
Cellular Immunology, 80:223-229 (1983).
Nature, 309:56-59 (1984).
J. Exp. Med., 160:772-787 (1984).
Cellular Immunology, 48:433-436 (1979).
The New England Journal of Medicine, 311(22):1413 (1984).
Proc. Natl. Acad. Sci., U.S.A., 81:7907-7911 (1984).
Nucleic Acid Res., 13(16)L5869-5882 (1985).
Nature, 304:449-451 (1983).
Cellular Immunology, 63:164-176 (1981).
J. Exp. Med., 150:709-714 (1979).
J. of Immunology, 130(6):2708-2714 (1983).
J. of Immunology, 132(3):1311-1316 (1984).
Nature, 314:266-268 (1985).
Nature, 312:458-462 (1984).
Biochemical and Biophysical Research Communications, 14(1):285-291 (1986).
J. Exp. Med., 161:490-502 (1985).
J. Exp. Med., 164:237-250 (1986).
J. of Immunology, 135(6):3962-3968 (1985).
J. of Immunology, 136(7):2483-2485 (1986).
J. of Immunology, 136(7):2492-2497 (1986).
J. of Immunology, 136(9):3304-3310 (1986).
Immunology Today, 7(2):45-56 (1986).
Jpn. J. Cancer Res. (Gann), 77:767-773 (1986).
Proceedings of AACR, 26:269 and 1058 (1985).
The Physiologic, Metobolic, and Immunologic Actions of interleukin-1: (Proceedings of a Symposium Held in Ann Arbor, Michigan, Jun. 4-6, 1985), pp. 253-262, Alan R. Liss, Inc., New York.
Eur. J. Immunol., 14:898-901 (1984).
Bio/Technology, 4:1078-1082 (1986).
Clin. Exp. Immunol., 55:295-302 (1984).
Arthritis and Rheumatism, 26(8):975-983 (1983).
Arthritis and Rheumatism, 28(8):853-862 (1985).
Immunological Rev., 63:51-72 (1982).
J. of Immunol., 136(8):3098-3102 (1986).
J. Clin. Invest., 79:48-51 (1987).
6th International Congress of Immunology, Abstracts, Jul. 6-11, 1986, Toronto, Canada, pp. 343-346, 349, 350-354 (particularly Theme Nos. 3.31.14, 3.31.22, 3.31.43, 3.31.39, 3.31.40, 3.31.38 and 3.32.23).
Metabolism, 23, Extra Ed. "Immunology '86", pp. 97-104 (1986).
Biochemical and Biophysical Research Communications, 143(1):345-352 (1987).
Medical Immunology, 12(6):753-760 (1986).
Proc. Jap. Soc. Immunol., 16:167 and 173 (1986).
Biochemistry, 58(8):840 (1986).
Jpn. J. Clin. Immunol., 9(5):330-332 (1986).
J. Exp. Med., 162:790-801 (1985).
Wingfield et al, Eur. J. Biochem., 160:491-497 (1986).
Meyers, J. Biol. Chem., 262:11176-11181 (1987).
Narachi et al, J. Biol. Chem, 262:13107-13110 (1987).
Arakawa et al, Protein Engineering, 3:721-724 (1990).
Yamagishi et al, Protein Engineering, 3:713-719 (1990).
Perry et al, Science, 226:555-557 (1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DNA encoding interleukin IL-1.beta. mutant does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA encoding interleukin IL-1.beta. mutant, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA encoding interleukin IL-1.beta. mutant will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-178424

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.