DNA encoding infectious rubella virus

Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses

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536 2372, 4352351, 4353201, C12N 1500, C12N 700, C12N 1540, C12N 1563

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054398142

ABSTRACT:
The entire rubella virus genomic RNA has been sequenced. An infectious cDNA clone has been constructed. Mutants of this clone that are rendered non-pathogenic are used as vaccines to vaccinate humans, including pregnant or older women, with decreased risk of causing fetal infection, autoimmune disease or neurological symptoms.

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