Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1993-07-19
1995-08-08
Mosher, Mary E.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
536 2372, 4352351, 4353201, C12N 1500, C12N 700, C12N 1540, C12N 1563
Patent
active
054398142
ABSTRACT:
The entire rubella virus genomic RNA has been sequenced. An infectious cDNA clone has been constructed. Mutants of this clone that are rendered non-pathogenic are used as vaccines to vaccinate humans, including pregnant or older women, with decreased risk of causing fetal infection, autoimmune disease or neurological symptoms.
REFERENCES:
Callahan, P. L. et al. 1985. Proc. Natl. Acad. Sci. USA vol. 82 pp. 732-736.
Cunningham, A. L. et al. 1985. J. Infect. Dis. vol. 15 pp. 638-645.
Mizutani, S. et al. 1985. J. Virol. vol. 56 pp. 628-632.
Ahlquist, P. et al. 1984. Proc. Natl. Acad. Sci. USA vol. 91 pp. 7066-7070.
Ahlquist, P. et al 1984. J. Mol. Biol. vol. 172 pp. 369-383.
Ahlquist, P. et al. 1984. Mol. Cell. Biol. vol. 4 pp. 2876-2882.
Ou, J. H. et al. 1983. J. Mol. Biol. vol. 168 pp. 1-15.
Frey, T. K. et al. 1989. Virol. vol. 168 pp. 191-194.
Niesters, H. G. M. et al. 1990. J. Virol. vol. 64 pp. 4162-4168.
Weibel, R. E. et al. 1980, Proc. Soc. Exp. Biol. Med. vol 165, pp. 44-49.
Waxham and Wolinsky, Virology 126:194-203 (1983).
Oker-Blom, et al., J. Virol. 46:964-973 (1983).
Waxham and Wolinsky, Virology 143:153-165 (1985).
Green and Dorsett, J. Virol. 57:893-898 (1986).
Oker-Blom, J. Virol. 51:354-358 (1984).
Rice, et al., Virology 61:3809-3819 (1987).
Frey, et al., Virology 154:228-232 (1986).
Nakhasi, et al. J. Biol. Chem. 261:16616-16621 (1986).
Clarke, et al. Nucleic Acids Res. 15:3041-3057 (1987).
Vidgren, et al., J. gen. Virol. 68:2347-2357 (1987).
Takkinen, et al. J. gen. Virol. 69:603-612 (1988).
Frey and Marr, Gene 62:85-99 (1988).
Dominguez, et al. Virology 177:225-238 (Jul., 1990).
Ballart, I. et al. 1991, EMBO J. vol. 10 (11) p. 3558.
Hovi, T. et al. 1970. Virology vol. 42 pp. 1-8.
Zheng, D. et al. 1989. Gene vol. 82 pp. 343-349.
Davis, N. L. et al. 1989. Virology vol. 171 pp. 189-204.
Dominguez Geraldina
Frey Teryl K.
Wang Chin-Yen
Georgia State Research Foundation, Inc.
Mosher Mary E.
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