Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1992-06-09
1994-04-26
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
536 2372, 4352523, 43525231, 43525233, 43525411, 43525421, 4353201, C12N 1538, C12N 510, C12N 119, C12N 121
Patent
active
053066359
ABSTRACT:
A gene of varicella-zoster virus (VZV) which encodes immunogenic outer surface viral proteins has been identified by DNA sequence analysis. Antibodies directed against peptides imputed from the DNA sequence can react with the glycoprotein, which itself is reactive with neutralizing antibodies. The amino-terminal sequence of the purified glycoprotein is identical to a portion of the amino acid sequence imputed from the DNA sequence. This glycoprotein is useful for the preparation of a vaccine against VZV.
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Davison Andrew J.
Ellis Ronald W.
Keller Paul M.
Lowe Robert S.
Riemen Mark W.
Bencen Gerard H.
Matukaitis Paul D.
Merck & Co. , Inc.
Mosher Mary E.
Schwartz Richard A.
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