DNA encoding IL-10-like homologue; related reagents

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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435 695, 4352523, 4353201, 536 235, 536 243, C12N 1524

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active

059898674

ABSTRACT:
Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.

REFERENCES:
patent: 5231012 (1993-07-01), Mosmann et al.
Helene M. Martin, et al., Gene159(2):187-191, 1995. "Cloning and characterisation of an ovine interleukin-10-encoding cDNA".
Anthony R. Mire-Sluis, et al., Journal of Immunological Methods, 187(2):191-199, 1995. "Quantitative cell line based bioassays for human cytokines".
Jan E. de Vries and Rene de Waal Malefyt, Interleukin 10, R.G. Landes Company: Austin, Texas, 1995.
G.S. Hudson, et al., GenBank, Accession No. M11924, pp. 1-5, Sep. 1, 1988. "The short unique region of the B95-8 Epstein-Barr virus genome".
Kevin W. Moore, et al., GenBank, Accession No. M37897, pp. 1-2, Jun. 12, 1991. "Homology of cytokine sythesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI".
H.-J. Rode, et al., GenBank, Accession No. L08504, p. 1, Aug. 2, 1993. "The genome of equine herpesvirus type 2 harbors an interleukin 10 (IL10)-like gene".
P. Vieira, et al., GenBank, Accession No. M57627, pp. 1-2, Mar. 7, 1995. "Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI".
Adams et al Accession # B69652.
Adams et al Accession # B48149.

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