DNA encoding hyaluronan synthase from Pasteurella multocida...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

Reexamination Certificate

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C435S252300, C435S254110, C435S069100, C435S193000, C536S023200

Reexamination Certificate

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06987023

ABSTRACT:
The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically activePasturella multocidahyaluronate synthase (PmHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan. The present invention also relates to the use of the PmHAS in constructing “knock-out” mutant strains ofP. multocidafor use in vaccinations. The present invention further relates to the use of the PmHAS in diagnostic tests in the field determinations of livestockP. multocidainfection.

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