DNA encoding horseshoe crab amebocyte lysate factor G subunit A

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

536 251, C07H 2102, C07H 2104

Patent

active

060779462

ABSTRACT:
This invention relates to a DNA shown by SEQ ID No. 1 and an amino acid sequence coded by said DNA. This invention also relates to a DNA and an amino acid sequence of subunit a of (1.fwdarw.3)-.beta.-glucan sensitive factor derived from amebocytes of horseshoe crab and have potent affinity to (1.fwdarw.3)-.beta.-D-glucan in cell walls of fungi. Therefore, the invention is useful for the diagnosis of fungal diseases and as antimicrobial or eradicating agent of fungi in combination with an antifungal agent.

REFERENCES:
patent: 4107077 (1978-08-01), Sullivan, et al.
patent: 4188264 (1980-02-01), Iwanaga et al.
patent: 4495294 (1985-01-01), Nakahara et al.
patent: 5047353 (1991-09-01), Tsuchiya et al.
patent: 5155032 (1992-10-01), Tanaka et al.
patent: 5179006 (1993-01-01), Matuura et al.
patent: 5316911 (1994-05-01), Baek et al.
patent: 5318893 (1994-06-01), Matuura et al.
patent: 5389547 (1995-02-01), Tanaka et al.
Kang, A.S. et al.; "Antibody redesign by chain shuffling from random combinatorial immunoglobulin libraries" Proc. Natl. Acad. Sci. USA, vol. 88, Dec. 1991, pp. 11120-11123.
Qabar, A.N. et al.; "Hierarchy of globin complexes" Journal of Molecular Biology, vol. 222, 1991, pp. 1109-1129.
Muta, T. et al.; "Limulus factor C" Journal of Biological Chemistry, vol. 266, No. 10, Apr. 5, 1991, pp. 6554-6561.
Noriaki et al., "Horseshoe Crab (1,3)-.beta.-D-Glucan-Sensitive Coagulation Factor G", The Journal of Biological Chemistry, 269, No. 2:1370-1374 (1994).
Sadaaki Iwanaga et al., "Role of Hemocyte-Derived Granular Components in Invertebrate Defense", Annals of the New York Academy of Sciences, 712:102-116 (1994).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

DNA encoding horseshoe crab amebocyte lysate factor G subunit A does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA encoding horseshoe crab amebocyte lysate factor G subunit A, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA encoding horseshoe crab amebocyte lysate factor G subunit A will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1854562

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.