Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing organic compound containing a metal or atom other...
Patent
1995-07-24
1998-06-30
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing organic compound containing a metal or atom other...
435 691, 4351723, 435193, 4352523, 43525233, 4353201, 435832, 536 232, C12P 900, C12P 2106, C12N 910, C07H 2104
Patent
active
057732655
ABSTRACT:
Heptaprenyl diphosphate (HDP)-synthetase derived from Bacillus stearothermophilus which enzymes have the amino acid sequences shown as SEQ ID NOs: 1 to 3; 1 and 2; 2 and 3; or 1 and 3, DNA encoding them, and a method of producing the enzymes.
According to the invention it is possible to industrially produce HDP-synthesizing enzyme and HPD.
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Summary of 67th Meeting of Japanese Biochemical Society No. 1728 (1994) (English Translation).
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J. Biochem., 113:3, pp. 355-363, Mar. 1993, Tokyo JP, "Thermostable Farnesyl Diphosphate Synthase . . . Overproduction and Purification", T. Koyama, et al. (Abstract).
FEBS Letters, 161:2, pp. 257-260, Sep. 19, 1983, Amsterdam NL, "Essential Protein Factors for Polyprenyl Pyrophosphase Synthetases . . . ", H. Fuji, et al.
J. Biochem., 270:31, pp. 18396-18400, Aug. 1995, Maryland US, "Molecular Cloning and Nucleotide Sequences . . . Heptaprenyl Diphosphate Synthesis", A. Koike-Takeshita, et al.
Koyama et al. (1994) Tennen Yuki Kagobutsu Toronkai Koen Yoshishu, 36th, 167-174 (abstract).
Koike Ayumi
Koyama Tanetoshi
Obata Shusei
Ogura Kyozo
Slobodyansky Elizabeth
Toyota Jidosha & Kabushiki Kaisha
Wax Robert A.
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