Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1994-05-26
1996-01-16
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
435188, 435189, 435 691, 4352523, 4352541, 4352542, 4352552, 536 221, 536 231, 536 237, 536 2374, C12N 910, C12N 996, C12N 114, C12P 2106
Patent
active
054847249
ABSTRACT:
The DNA encoding glucan synthesis gene 1 (GLS1) is cloned and used in an in vitro assay to screen for compounds that modulate 1,3.beta.-D glucan synthase activity.
REFERENCES:
Breuder, Tamara et al., "Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strain", Proc. Natl. Acad. Sci. USA, vol. 91, pp. 5372-5376, Jun. 1994.
Koonin, Eugene et al., "Yeast chromosome III: New Gene Functions", The EMBO Journal, vol. 13, No. 3, pp. 493-503, 1994.
Clemas Joseph A.
El-Sherbeini Mohamed
Carty Christine E.
Kim Hyosuk
Matukaitis Paul D.
Merck & Co. , Inc.
Tribble Jack L.
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