DNA encoding for a protein containing the extracellular domain o

Details DNA encoding for a protein containing the extracellular domain o DNA encoding for a protein containing the extracellular domain o

1995-06-07

1999-02-23

Caputa, Anthony C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 435362, 435365, 4353651, 435367, 4352523, 43525233, 43525411, 536 235, C12N 1512, C12N 1519, C12N 1563, C07H 2104

Patent

active

058742506

ABSTRACT:
The present invention relates to a protein containing the extracellular domain of LAG-3, and DNA sequences coding for the protein and the pharmaceutical and biological uses of the protein.

REFERENCES:
patent: 5109123 (1992-04-01), Reinherz et al.
Lazar Mol. Cell Biol 8(3):1247-52 Mar. 1988.
Burgess J. Cell Biol 11:2129-38 Nov. 1990.
Triebel, et al., J. Exp. Med., 171:1393-1405, May 1990.
Chang, N.T. et al., Chemical Abstracts 102:181-182, 216258n (1985).
Jongstra, J. et al., J. Exp. Med. 165:601-614 (1987).
Staunton, D.E. et al., The EMBO Journal 6(12):3695-3701 (1987).
Amzel, L.M. and Poljak, R.J., "Three-Dimensional Structure of Immunoglobus", Ann. Rev. Biochem. 48:961-997 (1979).
Aviv, H. et al., "Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose", Proc. Natl. Acad. Sci. USA 69(6):1408-1412 (Jun. 1972).
Bowie et al., "Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions", Science 247:1306-1310 (Mar. 1990).
Byrn, R.A. et al., "Biological properties of a CD4 immunoadhesin", Nature 334:667-670 (Apr. 12, 1990).
Dariavach P. et al., "Human immunoglobulin C.sub..lambda. 6 encodes the Kern .sup.+ Oz.sup.- .lambda. chain and C.sub..lambda. 4 and C.sub..lambda. 5 are pseudogenes", Proc. Natl. Acad. Sci. USA 84:9074-9078 (Dec. 1987).
Davis, M. M. et al., "Cell-type-specific cDNA probes and the murine I region: The localization and orientation of A.sub..alpha..sup.a " Proc. Natl. Acad. Sci. USA 81:2194-2198 (Apr. 1984).
Dayhoff, M.O. et al., "Establishing Homologies in Protein Sequences", Methods Enzymol. 91:524-45 (1983).
Feinberg, A.P. et al., "A Technique for Radiolabeling DNA Restriction Endonclease Fragments to High Specific Activity", Anal. Biochem. 132:6-13 (1983).
Goding, "Production of Monoclonal Antibodies", Chapter 3 in: Goding, Academic Press, Monoclonal Antibodies: Principles and Practices:59-103 (1986).
Goding, "Purification, Fragmentation and Isotopic Labelling of Monoclonal Antibodies", Chapter 4 in: Goding, Academic Press, Monoclonal Antibodies: Principles and Practices: 104-141 (1986).
Goding, "Generation of Conventional Antibodies", Chapter 8 in: Goding, Academic Press, Monoclonal Antibodies: Principles and Practices: 281-293 (1986).
Gubler, U. and Hoffman,B.J., "A simple and very efficient method for generating cDNA libraries", Gene. 25:263-269 (1983).
Harris, W.J. et al., "Therapeutic antibodies--the coming of age", TibTech 11:42-44 (Feb. 1993).
Hart, C.E. et al., "Human Chromosome 12 is Required for Elevated HIV-1 Expression in Human Haster Hybrid Cells", Science 246:488-491 (Oct. 27, 1989).
Huynh, T.V. et al., "Constructing and Screening cDNA Libraries in .lambda.gt10 and .lambda.gt11" D. Glover (ed), IRL Press. Oxford, UK, DNA cloning: A practical approach: 49-78.
Kirszbaum, L. et al., "The .alpha.-Chain of Murine CD8 Lacks an Invariant Ig-Like Disulfide Bond but Contains a Unique Intrachain Loop Instead", J. Immunol. 142(11):3931-3936 (Jun. 1, 1989).
Lesk, A.M. and Chothia, C., "Evolution of Proteins Formed by .beta.-Sheets", J. Mol. Biol. 160:325-342 (1982).
Luckow, V.A. et al., "Trends in the Development of Baculovirus Expression Vectors", Bio/Technology 6:47-55 (Jan. 1988).
Maddon, P.J. et al., "Structure and Expression of the Human and Mouse T4 Genes", Proc. Natl. Acad. Sci. USA 84:9155-9159 (1987).
Marlin, S.D. et al., "A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection", Nature 344:70-72 (Mar. 1, 1990).
Mechler, B. et al., "Membrane-bound Ribosomes of Myeloma Cells IV. mRNA Complexity of Free and Membrane-bound Polysomes", J. Cell. Biol. 88:29-36 (Jan. 1981).
Moingeon, P. et al., "A unique T-cell receptor complex expressed on human fetal lymphocytes displaying natural-killer-like activity", Nature 323:638-640 (Oct. 16, 1986).
Nowill, A. et al., "Natural Killer Clones Derived From Fetal (25wk) Blood", J. Exp. Med. 163:1601-1606 (Jun. 1986).
Ratner, L. et al., "Complete nucleotide sequence of the AIDS virus, HTLV-III", Nature 313:277-284 (Jan. 24, 1985).
Ruoslahti, E. et al., "Arg-Gly-Asp: A Versatile Cell Recognition Signal", Cell 44:517-518 (Feb. 28, 1986).
Ryu, S.-E. et al., "Crystal structure of an HIV-binding recombinant fragment of human CD4", Nature 348:419-426 (Nov. 29, 1990).
Sanger, F. et al., "DNA sequencing with chain-terminating inhibitors", Proc. Natl. Acad. Sci. USA 74(12):5463-7 (Dec. 1977).
Santoni, M.J. et al., "Differential exon usage involving an unusual splicing mechanism generates at least eight types of NCAM cDNA in mouse brain", EMBO J. 8(2):385-392 (1989).
Seed, B., "An LFA-3-cDNA encodes a phospholipid linked membrane protein homologous to its receptor CD2", Nature 329:840-842 (Oct. 29, 1987).
Staunton, D.E. et al., "The Arrangement of the Immunoglobulin-like Domains of ICAM-1 and the Binding Sites for LFA-1", Cell 61:243-254 (Apr. 20, 1990).
Triebel, F. et al., "Cloned human CD3 .sup.- lymphocytes with natural killer-like activity do not express nor rearrange T cell receptor gamma genes", Eur. J. Immunol. 17:1209-1212 (1987).
Waldmann, T. A. et al., "Monoclonal Antibodies in Diagnosis and Therapy", Science 252:1657-1662 (Jun. 21, 1991).
Wang, J. et al., "Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains", Nature 348:411-418 (Nov. 29,1990).
Wegner, C.D. et al., "Intercellular Adhesion Molecule-1 (ICAM-1) in the Pathogenesis of Asthma", Science 247:456-459 (Jan. 26, 1990).
Williams, A.F., "A year in the life of the immunoglobulin superfamily", Immunol. Today 8(10):298-303 (1987).
Williams, A.F. et al., "The Immunoglobulin Superfamily--Domains for Cell Surface Recognition", Ann. Rev. Immunol. 6:381-405 (1988).
Yourno, J. et al., "Nucleotide Sequence Analysis of the env Gene of a New Zairian Isolate of HIV-1", AIDS Res. Hum. Retroviruses 4(3):165-173 (1988).
Ythier, A. et al., "Generation of Monoclonal Antibodies Blocking Cytotoxic Reactions by Human NK Clones: Further Characterization of an 40/80-kDa Target Cell Receptor", Cell Immunol. 99:150-159 (1986).

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