DNA encoding fibronectin and fibrinogen binding protein from gro

Chemistry: molecular biology and microbiology – Vector – per se

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435325, 536 237, C12N 1500, C12N 500, C07H 2104

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active

059104414

ABSTRACT:
This invention relates to a novel fibrinogen and fibronectin binding protein from group A streptococci, and the DNA encoding the protein. The protein and its DNA are useful in the preparation of compositions for the diagnosis, treatment, and prevention of streptococcal infection.

REFERENCES:
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Hanski, E. et al., "Expression of Protein F, the Fibronectin-Binding Protein of Streptococcus pyogenesJRS4, in Heterologous Streptococcal and Enterococcal Strains Promotes Their Adherence to Respiratory Epithelial Cells", Infect. Immun. (1992) 60:5119-5125.
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