DNA encoding epithelium-derived T-cell factor

Details DNA encoding epithelium-derived T-cell factor DNA encoding epithelium-derived T-cell factor

1993-03-08

1996-09-03

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 4352401, 536 2352, 530351, C12P 2106, C12N 1524, C12N 510, C07K 1454

Patent

active

055523030

ABSTRACT:
There is disclosed a mammalian epithelium-derived T-cell factor (EFT) polypeptide, derivatives thereof, DNA sequences, recombinant DNA molecules and transformed host cells that produce ETF polypeptides. More particularly, this invention provides isolated mammalian ETF polypeptides and derivatives thereof that regulate events in T-lymphocyte proliferation.

REFERENCES:
McMahan et al., "A Novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types", EMBO J. 10:2821-2832 (1991).
Nishimura et al 1991 FEBS Lett 281:167-169.
Coleman et al, J. Immunol 138, 1987, pp. 3314-3318.
Cornaglia-Ferraris et al, Lymphokine Res. 4(3) 1985, pp. 251-263.
Ogata et al, J. Leukocyte Biol 49, 1989, pp. 69-78.

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