DNA encoding endothelial monocyte activating polypeptide III

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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530350, 530351, 435 691, 435 695, 4352523, 4353201, 536 235, C12P 2102, C12N 1519, C12N 1563, C07K 1452

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active

060134836

ABSTRACT:
A human EMAP III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for preventing and/or treating neoplasia. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.

REFERENCES:
patent: 5147638 (1992-09-01), Esmon et al.
Kao et al. Journal of Biological Chemistry. vol 269. No. 40. Characterization of a Novel Tumor-derived Cytokine. pp. 25106-25119, Oct. 7, 1994.

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