DNA encoding ENA-78, a neutrophil activating factor

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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536 235, 4353201, 4352523, 435 691, 435 695, 530350, C12N 1519, C12N 1566, C12N 510

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active

054016517

ABSTRACT:
The invention relates to a novel factor comprising a polypeptide denominated ENA-78, said factor being derived from epithelial cells and having the ability to activate neutrophils, as well as DNA coding for such factors, methods of treating neutrophil deficiencies, methods of identifying inhibitors of ENA-78 using a novel assay, the inhibitors identified by such an assay, and methods for treating acute and chronic lung disorders using such inhibitors.

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