DNA encoding Derf II, the major mite allergen, host cells contai

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

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4242751, 4242761, 435 693, 435 697, 4352523, 43525233, 4352542, 4352551, 4353201, 536 235, A61K 3935, C07H 2104, C12N 1512, C12N 1563, C12N 1565, C12N 121, C12N 115, C12P 2100

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057980993

ABSTRACT:
The invention provides a DNA encoding at least one part of genetic information of protein which has biochemical and immunological properties of a major allergen of Dermatophagoides farinae (Derf II).

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Allergens of the House Dust Mite Dermatophagoides farinae. II. Immunological Characterization of Four Allergenic Molecules Int. Archs Allergy appl. Immun. (1989) 88:173-175.
Yasueda, et al. Comparative Analysis of Physicochemical and Immunochemical Properties of the Two Major Allergens from Dermatophagoides pteronyssinus and the corresponding Allergens from Dermatophagoides farinae Int. Archs Allergy appl. Immun. 88:402-407 (1989).
Chua, et al. Isolation of cDNA Coding for the Major Mite Allergen Der p II by IgE Plaque Immunoassay Int. Arch. Allergy Appl. Immunol 91:118-123 (1990).
Chua, et al. "Expression of Dermatophagoides pteronyssinus Allergen, Der p II, in Escherichia coli and the Binding Studies with Human IgE" Int. Arch. Allergy Appl. Immunol. 1990; 91:124-129.
Greene, et al. Antigenic Analysis of Group I House Dust Mite Allergens Using Random Fragments of Der p I Expressed by Recombinant DNA Libraries Int. Arch Allergy Appl. Immunol 1990: 92: 30-28.
Yuuki, et al. Cloning and Sequencing of cDNAS Corresponding to Mite Major Allergen Der f II Jpn. J. Allerg. (1990) pp. 557-561.
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