Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1997-07-25
1999-11-09
Hutzell, Paula K.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 53038824, 5303881, 530350, C07K 1600
Patent
active
059817127
ABSTRACT:
This invention provides for nucleotide sequences that encode CAIR proteins correlated with cellular resistance to carboxyamido-triazole (CAI) and functionally equivalent compounds. The invention further provides for methods of detecting CAI resistance in biological samples and for cell lines that grow and proliferate in the presence of CAI and functionally equivalent compounds.
REFERENCES:
patent: 5359078 (1994-10-01), Kohn et al.
patent: 5652223 (1997-07-01), Kohn et al.
Asubel et al. (eds.) (1988) Current Protocols in Molecular Biology, John Wiley & Sons, New York, pp. 6.3.2-6.3.6, 6.4.1-6.4.3, and A.2.3.
Federal Res. in Progress (Dialog File 265) "Signal Transduction Therapy," Basic Science, Princ. Inst., Kohn, E.C., Research Summary, Identification IB01CZ09163-06.
Forgue-Lafitte et al. (1992) Cancer Res. 52:6827-6831.
Hampson et al. (1992) Nuc. Acids Res. 20:2899.
Kohn et al. (1994) Cancer Res. 54:935-942.
Kohn & Liotta (1990) J. Nat. Cancer Inst. 82:54-60.
Kim et al. (1994) Proc. Am. Assoc. for Cancer Res. 35:591.
Felder et al. (1991) J. Pharm. Exp. Therap. 257:967-971.
Gusovsky et al. (1993) J. Bio. Chem. 268:7768-7772.
Merritt et al. (1990) Biochem. J. 271:515-522.
Cicchetti et al. (1992) Science 257:803-806.
Ren et al. (1993) Science 259:1157-1161.
Kappeler et al. (1994) J. Biol. Chem. 269(3):1927-1933.
Koch et al. (1991) Science 252:668-674.
Kim Young Sook
Kohn Elise C.
Liotta Lance A.
Basi Nirmar S.
Hutzell Paula K.
The United States of America as represented by the Department of
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