DNA encoding CAI resistance proteins and uses thereof

Details DNA encoding CAI resistance proteins and uses thereof DNA encoding CAI resistance proteins and uses thereof

1994-03-14

1997-07-29

Low, Christopher S. F.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 231, 536 232, 536 235, 435 911, 435 915, 4351723, 4353201, 935 9, 935 14, A01N 4304, A61K 3170, C12N 510

Patent

active

056522231

ABSTRACT:
This invention provides for nucleotide sequences that encode CAIR proteins correlated with cellular resistance to carboxyamido-triazole (CAI) and functionally equivalent compounds. The invention further provides for methods of detecting CAI resistance in biological samples and for cell lines that grow and proliferate in the presence of CAI and functionally equivalent compounds.

REFERENCES:
patent: 5359078 (1994-10-01), Kohn et al.
Asubel et al. (eds.), 1988, in: Current Protocols In Molecular Biology, John Wiley & Sons, New York, pp. 6.3.2 to 6.3.6, 6.4.1 to 6.4.3, and A.2.3.
Federal Res. in Progress (Dialog File 265)--"Signal Transduction Therapy Basic Science. Princ. Invest.", Kohn, E.C., Research Summary, Identification 1Z01CB09163-06.
Baker et al. 1987. in: Fourth Edition. The Study of Biology. Addison-Wesley Publ. Co., Reading MA., p. 520.
Forgue-Lafitte et al. 1992 Cancer Res. 52, 6827-6831.
Hampson et al. 1992 Nuc. Acids Res. 20, 2899.
Kohn, et al., Cancer Res., 54: 935-942 (1994).
Kohn & Liotta, J. Nat. Cancer Inst., 82: 54-60 (1990).
Kim, et al., Proc. Am. Assoc. for Cancer Res., 35: 591 (1994).
Felder, et al., J. Pharm. Exp. Therap., 257: 967-971 (1991).
Gusovsky, et al., J. Bio. Chem., 268: 7768-7772 (1993).
Merritt, et al., Biochem. J., 271: 515-522 (1990).
Cicchetti, et al., Science, 257: 803-806 (1992).
Ren, et al., Science, 259: 1157-1161 (1993).
Kapeller, et al., J. Biol. Chem., 269:3 1927-1933 (1994).
Koch, et al., Science, 252: 668-674 (1991).

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