Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-10-07
2000-10-24
Kunz, Gary L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 691, 435 703, 435 713, 435 712, 435471, 435325, 4352523, 4353201, 536 235, 536 243, 530350, C12N 1512, C12N 1563, C12N 510, C07K 1447, C07K 14705
Patent
active
061365599
ABSTRACT:
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
REFERENCES:
patent: 5817480 (1998-10-01), Murry et al.
patent: 5882893 (1999-03-01), Goodearl
Erlander Mark
Huvar Arne
Lovenberg Timothy W.
Pyati Jayashree
Hamud Fozia
Kunz Gary L.
Ortho Pharmaceutical Corporation
Wallen III John W.
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