Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease
Patent
1997-10-27
2000-12-26
Hobbs, Lisa J.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Transferase other than ribonuclease
435 6, 4352523, 43525411, 4353201, 435325, 435440, 536 232, C12N 910, C12N 120, C12Q 168, C07H 2104
Patent
active
06165762&
ABSTRACT:
The invention provides apt polypeptides and DNA (RNA) encoding apt polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing apt polypeptides to screen for antibacterial compounds.
REFERENCES:
SwissProt Submission; Accession Number P07672; Direct Submission; Apr. 1, 1988.
Hershey, et al., "Nucleotide Sequence and Deduced Amino Acid Sequence ofEscherichia Coli Adenine Phosphoribosyl-Transferase and Comparison With Other Analogous Enzymes." Gene, vol. 43, pp. 287-293, (1986).
Hochstadt-Ozer, et al., "Adenine Phosphoribosyltransferase from Escherichia coli." J. Biol. Chem., vol. 246, pp. 558-567, (1971).
Black Michael Terence
Brown James Raymond
Hodgson John Edward
Knowles David Justin Charles
Lonetto Michael Arthur
Deibert Thomas S.
Gimmi Edward R.
Hobbs Lisa J.
King William T.
SmithKline Beecham Corporation
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