Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-08-28
1999-03-23
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 536 235, 536 2431, C12N 1519, C12N 1564
Patent
active
058857982
ABSTRACT:
The present invention provides novel monocyte activating cytokine (MAC) and a polynucleotide encoding MAC. The invention also provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding MAC. The invention also provides for the production and use of substantially purified MAC in pharmaceutical compositions for the treatment of cancer and disease of the immune system. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts encoding MAC and antibodies which specifically bind to MAC.
REFERENCES:
Kao et al., "Characterization of a Novel Tumor-derived Cytokine," The Journal of Biological Chemistry, 269(40): 25106-25119 (1994) (GI 498910).
Ribas de Pouplana et al., "Evidence that two present-day components needed for the genetic code appeared after nucleated cells separated from eubacteria," Proc. Natl. Acad. Sci. USA, 93:166-170 (1996) (GI1184699).
Kao et al., "A Peptide Derived from the Amino Terminus of Endothelial-Monocyte-activating Polypeptide...," The Journal of Biological Chemistry, 269(13):9774-9782 (1994).
Kao et al J. Brol. Chem. vol. 269(40): pp. 25106-25119 1994.
Au-Young Janice
Bandman Olga
Coleman Roger
Murry Lynn E.
Basham Daryl A.
Billings Lucy J.
Incyte Pharmaceuticals Inc.
Walsh Stephen
LandOfFree
DNA encoding a monocyte activating cytokine does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with DNA encoding a monocyte activating cytokine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA encoding a monocyte activating cytokine will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2124112