DNA encoding a macadamia integrifolia anti-microbial...

Multicellular living organisms and unmodified parts thereof and – Plant – seedling – plant seed – or plant part – per se – Higher plant – seedling – plant seed – or plant part

Reexamination Certificate

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C435S418000, C536S063000

Reexamination Certificate

active

06909032

ABSTRACT:
The subject invention relates to DNA encoding an anti-microbial protein fromMacadamia integrifoliaand variants of the protein that are less sensitive to Ca++. The invention further relates to constructs comprising the DNA, and host cells, plants and plant material comprising such constructs.

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De Bolle, M. et al.,Mirabilis Jalapa Antibacterial Peptides and Raphanus Sativus Antifungal Proteins: A Comparative Study of Their Structure and Biological Activities, Mechanisms of Plant Defense, 1993, pp. 433-436.
Byler et al.,Neotropical Natural Products: Antimicrobial Activity of Essential Oils of Flora From Monteverde, Costa Rica, The Journal of the Alabama Academy of Science, vol. 62, No. 2-3, Apr.-Jul. 1991, pp. 86-87.
Jacob et al.,Potential therapeutic applications of magainins and other antimicrobial agents of animal origin, Antimicrobial Peptides, 1994, pp. 197-223.

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