Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1994-12-02
1997-02-11
Walsh, Stephen G.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
4352523, 43525411, 4353201, 435348, 435365, 435369, 536 235, C07H 2100, C12N 1512, C12N 1563, C12N 510
Patent
active
056020244
ABSTRACT:
This invention provides an isolated nucleic acid molecule encoding a human Y5 receptor, an isolated protein which is a human Y5 receptor, vectors comprising an isolated nucleic acid molecule encoding a human Y5 receptor, mammalian cells comprising such vectors, antibodies directed to the human Y5 receptor, nucleic acid probes useful for detecting nucleic acid encoding human Y5 receptors, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human Y5 receptor, pharmaceutical compounds related to human Y5 receptors, and nonhuman transgenic animals which express DNA a normal or a mutant human Y5 receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human Y5 receptor.
Branchek Theresa
Gerald Christophe P. G.
Walker Mary W.
Weinshank Richard L.
Gucker Stephen
Synaptic Pharmaceutical Corporation
Walsh Stephen G.
White John P.
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