Chemistry: molecular biology and microbiology – Spore forming or isolating process
Patent
1995-01-09
1995-12-19
Allen, Marianne P.
Chemistry: molecular biology and microbiology
Spore forming or isolating process
536 235, 4351721, 530350, 935 9, C07H 2104, C12N 510, C12N 1512
Patent
active
054767822
ABSTRACT:
This invention provides an isolated nucleic acid molecule encoding a human 5-HT.sub.1E receptor, an isolated protein which is a human 5-HT.sub.1E receptor, vectors comprising an isolated nucleic acid molecule encoding a human 5-HT.sub.1E receptors, mammalian cells comprising such vectors, antibodies directed to the human 5-HT.sub.1E receptor, nucleic acid probes useful for detecting nucleic acid encoding human 5-H.sub.1E receptors, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human 5-HT.sub.1E receptor, pharmaceutical compounds related to human 5-HT.sub.1E receptors, and nonhuman transgenic animals which express DNA a normal or a mutant human 5-HT.sub.1E receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human 5-HT.sub.1E receptor.
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Branchek Theresa
Hartig Paul R.
Weinshank Richard L.
Allen Marianne P.
Spector Lorraine M.
Synaptic Pharmaceutical Corporation
White John P.
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