Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-02
1998-01-20
Walsh, Stephen
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
536 235, 4353201, 435325, C12P 2102, C12N 1512, C12N 1579, C12N 516
Patent
active
057100179
ABSTRACT:
Purified DNA encoding a Constitutive Activator of Retinoid acid response (CAR) receptors and the recombinant proteins expressed from such DNA are disclosed. The recombinant receptor polypeptides are members of the nuclear hormone receptor super family and are used to identify CAR ligands and CAR receptor binding sites and are also used to produce therapeutics. Antibodies specific for CAR receptor polypeptides are also disclosed.
REFERENCES:
patent: 4870009 (1989-09-01), Evans et al.
patent: 4981784 (1991-01-01), Evans et al.
patent: 5071773 (1991-12-01), Evans et al.
patent: 5077211 (1991-12-01), Yarosh
patent: 5183736 (1993-02-01), Pfahl et al.
patent: 5571696 (1996-11-01), Evans et al.
Evans, "The Steroid and Thyroid Hormone Receptor Superfamily", Science 240:889-895, 1988.
Fuller, "The Steroid Receptor Superfamily: Mechanisms of Diversity", FASEB 5:3092-3099, 1991.
Gebert et al., "High Frequency of Retinoic Acid Receptor B Abnormalities in Human Lung Cancer", Oncogene 6:1859-1868, 1991.
Kumar et al., "functional Domains of the Human Estrogen Receptor", Cell 51:941-951, 1987.
Baes Myriam I.
Moore David D.
Pal Michael D.
The General Hospital Corporation
Walsh Stephen
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