DNA encoding a basic fibroblast growth factor

Details DNA encoding a basic fibroblast growth factor DNA encoding a basic fibroblast growth factor

1990-04-05

1991-06-25

Moskowitz, Margaret

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530399, 435 694, 4353201, C12N 15018

Patent

active

050268392

ABSTRACT:
An isolated DNA sequence encoding an angiogenic factor protein consisting of a single-polypeptide-chain protein having at least one active site possessing mitotic and chemotactic activity and the ability to stimulate protease synthesis, wherein said protein consists of the amino acid sequence: ##STR1## In a preferred embodiment, the DNA sequence encodes basic fibroblast growth factor (bFGF).

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