DNA diagnostics for glaucoma

Details DNA diagnostics for glaucoma DNA diagnostics for glaucoma

1996-11-08

1999-07-20

Crouch, Deborah

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 2431, 536 235, 435 6, 435 912, C07H 2102, C07H 2104, C07H 1900, C07H 2100

Patent

active

059257482

ABSTRACT:
Methods and kits for diagnosing a subject with glaucoma or with a predisposition for developing glaucoma are disclosed.

REFERENCES:
patent: 5606043 (1997-02-01), Nguyen et al.
Escribano, J. et al. (1995) "Isolation and Characterization of Cell-Specific cDNA Clones from a Substractive Library of the Ocular Ciliary Body of a Single Normal Human Donor: Transcription and Synthesis of Plasma Proteins", J. Biochem., 118:921-931.
Ortega, J. et al. (1997), "Cloning and Characterization of Subtracted cDNAs from a Human Ciliary Body Library Encoding TIGR, a Protein Involved in Juvenile Open Angle Glaucoma with Homology to Myosin and Olfactomedin", FEBS Letters, 413:349-353.
Stone, Edwin M. et al. (1997) "Identification of a Gene that Causes Primary Open Angle Glaucoma", Science, 275:668-670.
Sunden, Sara L.F. et al. (1996) "Fine Mapping of the Autosomal Dominant Juvenile Open Angle Glaucoma (GLC1A) Region and Evaluation of Candidate Genes" Genome Res., 6:862-869; and International Search Report (PCT/US97/20702) Mar. 13, 1998.
"CHLC Report" (Newsletter), Cooperative Human Linkage Center, vol. 1, pp. 1-18, May 1993.
"Editorial: Genetic Associations of Glaucoma", British Journal of Ophthalmology, vol. 64, pp. 225-226, 1980.
Cotton, P., "Glaucoma Gene Mapped to Chromosome 1", JAMA, vol. 269, No. 21, p. 2715, Jun. 2, 1993.
Francois, J., "Genetics and Primary Open-Angle Glaucoma", Am. J. Ophthalmol., vol. 61, pp. 652-665, 1966.
Harris, D., "The Inheritance of Glaucoma: A Pedigree of Familial Glaucoma", Am. J. Ophthalmol., vol. 60, pp. 91-95, 1965.
Johnson, A.T. et al., "Clinical Features and Linkage Analysis of a Family with Autosomal Dominant Juvenile Glaucoma", Ophthalmology, vol. 100, No. 4, pp. 524-528, Apr. 1993.
Kolker, A.E., "Glaucoma Family Study: Ten-Year Follow-up (Preliminary Report)", Israel J. Med. Sci., vol. 8, No. 8-9, pp. 1357-1361, Aug.-Sep. 1972.
Leighton, D.A., "Survey of the First-degree Relatives of Glaucoma Patients", Trans. Ophthal. Soc. U.K. vol. 96, pp. 28-32, 1976.
Martin, J.P. and E.C. Zorab, "Familial Glaucoma in Nine Generations of a South Hampshire Family", Brit. J. Ophthal., pp. 536-542, 1974.
Miller, S.J.H. and G.D. Paterson, "Studies on Glaucoma Relatives", Brit. J. Ophthalmol., vol. 46, pp. 513-522, 1962.
Orita, M. et al., "Detection of Polymorphisms of Human DNA by Gel Electrophoresis as Single-Strand Conformation Polymorphisms", Proc. Natl. Acad. Sci. USA, vol. 86, pp. 2766-2770, Apr. 1989.
Perkins, E.S., "Family Studies in Glaucoma", Brit. J. Ophthal., vol. 58, pp. 529-535, 1974.
Richards, J.E. et al., "Mapping of a Gene for Autosomal Dominant Juvenile-Onset Open-Angle Glaucoma to Chromosome Iq", Am. J. Hum. Genet., vol. 54, pp. 62-70, 1994.
Sheffield, V.C., et al., "Attachment of a 40-Base-Pair G+C-Rich Sequence (GC-clamp) to Genomic DNA Fragments by the Polymerase Chain Reaction Results in Improved Detection to Single-Base Changes", Proc. Natl. Acad. Sci. USA, vol. 86, pp. 232-236, Jan. 1989.
Sheffield, V.C., et al., "Genetic Linkage of Familial Open Angle Glaucoma to Chromosome 1q21-q31", Nature Genetics, vol. 4, pp. 47-50, May 1993.
Weatherill, J.R. and Hart, C.T., "Familial Hypoplasia of the Iris Stroma Associated with Glaucoma" Brit. J. Ophthal., vol. 53, pp. 433-438, 1969.

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