DNA detector and DNA detection method

Details DNA detector and DNA detection method DNA detector and DNA detection method

1995-01-13

1996-05-14

Niebling, John

Chemistry: electrical and wave energy

Apparatus

Electrophoretic or electro-osmotic apparatus

204605, 204612, 2504581, 2504612, C25D 1300, C25B 700, C25B 100, G21K 500

Patent

active

055164099

ABSTRACT:
An electrophoresis apparatus for detecting samples migrating in migration portions includes a plurality of gel separation portions separate from one another and having respective ends disposed along a straight line, a plurality of migration portions equal in number to the gel separation portions and disposed along a straight line following respective ones of the gel separation portions, a light source for generating light which passes through the migration portions, the light propagating along a straight line extending through all of the migration portions, a plurality of optical fibers having respective first ends and respective second ends, the first ends of the optical fibers being disposed facing respective points where the light from the light source passes through respective ones of the migration portions, the optical fibers being equal in number to or greater in number than the migration portions, and an optical detector optically coupled to the second ends of the optical fibers for receiving light from the migration portions via the optical fibers.

REFERENCES:
patent: 4870004 (1989-09-01), Conroy et al.
patent: 5194915 (1993-03-01), Gilby
patent: 5312535 (1994-05-01), Waska et al.
Multiple-sheathflow capillary array DNA analyser.(NATURE . VO.361. 11 Feb. 1993.).
Capillary array electrophoresis: an approach to high-speed, high-throughput DNA sequencing.(NATURE . vol. 359. 10 Sep. 1992).
Preparation of Polyacrylamide Gel Filled Capillaries for Ultrahigh Resolution of Polynucleotides by Capillary Gel Electrophoresis. (1222, Analytical Chemistry. vol. 64, No. 11, Jun. 1, 1992.).

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