DNA containing the prolipoprotein signal peptidase gene

Details DNA containing the prolipoprotein signal peptidase gene DNA containing the prolipoprotein signal peptidase gene

1988-02-23

1990-05-29

Mays, Thomas D.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

4351723, 435212, 435220, 4352523, 435320, 435849, 536 27, 935 14, 935 29, 935 72, 935 73, C12N 120, C12N 1500, C07H 1512

Patent

active

049295594

ABSTRACT:
One of the E. coli strains of the Clarke and Carbon collection [Cell, 9, 91-99] has been found to contain a plasmid which we have isolated and termed pLC3-13, which contains genetic information coding for prolipoprotein signal peptidase. A 4.3 kb fragment containing this genetic information has been prepared, other plasmids have been prepared containing at least this fragment and strains of E. coli have been transformed thereby.

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P. Silver, W. Wickner, J. Bacteriol 154(569), (1983).
T. Date, W. Wickner, Proc. Natl. Acad. Sci. USA 78 (6106), (1981).
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P. B. Wolfe, W. Wickner, J. M. Goodman, J. Biol. Chem. 258(12073), (1983).
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