DNA constructs encoding CD4 fusion proteins

Details DNA constructs encoding CD4 fusion proteins DNA constructs encoding CD4 fusion proteins

1995-04-07

1998-12-08

Elliott, George C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 235, 536 245, 435 697, C12N 1512, C12N 100, C07H 2104, C07H 1473

Patent

active

058470964

ABSTRACT:
The subject invention relates to defective, interfering HIV particles and uses thereof. In particular, these particles encode a membrane bound receptor protein, as well as multitarget ribozymes, which together interfere with the production of infectious HIV by a host cell by downregulating the amount of HIV envelope protein on the surface of the cell as well as the amount of HIV genomic RNA.

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