DNA comprising lamb secretion signal sequence and mature IGF-1 s

Details DNA comprising lamb secretion signal sequence and mature IGF-1 s DNA comprising lamb secretion signal sequence and mature IGF-1 s

1995-05-31

1997-07-29

Jagannathan, Vasu S.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 697, 536 234, 536 2351, 530399, C12N 121, C12N 1518, C07K 1465

Patent

active

056521391

ABSTRACT:
A method for bacterially producing IGF-I is disclosed in which Gram-negative bacteria are caused to express a gene consisting of a lamB or ompF signal sequence operatively joined to a DNA sequence encoding IGF-I and producing IGF-I which is secreted into the periplasmic space of the bacteria.

REFERENCES:
patent: 4336336 (1982-06-01), Silhavy et al.
patent: 4411994 (1983-10-01), Gilbert et al.
patent: 4689406 (1987-08-01), Banks et al.
patent: 4738921 (1988-04-01), Belagaje et al.
patent: 4757013 (1988-07-01), Inouye et al.
patent: 5015573 (1991-05-01), Yarranton et al.
Ghrayeb et al., 1984, EMBOJ, 3:2437-2442.
Buell et al., 1985, Nucl. Acids. Res., 13:1923-1938.
Freudl et al., 1987, (Jan.), J. of Bacti., 169:66-71.
Nagahari et al., 1985, EMBOJ, 4:3589-3592.
Dunn et al., 1983, J. Mol. Biol., 166; pp. 504-505.
Brosius et al., 1985, Gene, 27:161-172.
Benson et al., 1984, Proc. Natl. Acad. Sci. USA, 81:3830-3834.
Nucleic Acids Research, vol. 14, pp. 7487-7500, (1986), Abrahmsen et al.
Nucleic Acids Research, vol. 12, pp. 5145-5164, (1984), Watson.
Nucleic Acids Research, vol. 11, pp. 1283-1294, (1983), Oshuye et al.
Wong et al. Gene 68: 193-203, 1988.
Hoffman et al. PNAS 82: 5107-5111, 1985.
Dunn et al. J. Mol. Biol. 166: 477-535, 1983.
Nilsson et al. Nuc. Acids Res. 13(4): 1151-1162, 1985.
Sjostrom et al. EMBO J. 6(3):823-831, 1987.

Affiliated with

Also associated with

Rating

DNA comprising lamb secretion signal sequence and mature IGF-1 s does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA comprising lamb secretion signal sequence and mature IGF-1 s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA comprising lamb secretion signal sequence and mature IGF-1 s will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-633024