DNA complementary to RNA of human leukemia virus

Details DNA complementary to RNA of human leukemia virus DNA complementary to RNA of human leukemia virus

1987-10-05

1988-10-18

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Vector, per se

4351723, 536 27, 935 6, 935 12, 935 32, C12N 1500, C07H 1512

Patent

active

047787562

ABSTRACT:
A viral genomic DNA and fragments thereof which are complementary to genomic RNA of human leukemia virus and a recombinant DNA molecules containing the genomic DNA or fragments thereof. The genomic DNA and fragments thereof and the recombinant DNA molecules are useful for the diagnosis, prevention and therapy of human leukemia.

REFERENCES:
Seiki et al, 1983, "Human Adult T-Cell Leukemia Virus: Complete Nucleotide Sequence of the Provirus Genome . . . ", Proc. Natl. Acad. Sci., v. 80, 3618-3622.
Yoshida et al, 1982, "Isolation and Characterization of Retrovirus from Cell Lines of Human T-Cell Leukemia . . . ", Proc. Natl. Acad. Sci., v. 79, 2031-2035.
Seiki et al, 1982, "Human Adult T-Cell Leukemia Virus: Molecular Cloning of the Provirus and the Unique Terminal Structure", Proc. Natl. Acad. Sci., v. 79, 6899-6902.
J. Virol., vol. 38 (1981), 688:703.
P.N.A.S., vol. 79 (1982), 5680:3.

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