DNA coding sequences for mevalonate Pyrophosphate decarboxylase

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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435 691, 435232, 4352523, 4353201, 435 772, C12N 1560, C12N 1570, C12N 988, G01N 3353

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058378391

ABSTRACT:
We have cloned and expressed the cDNA for human liver mevalonate pyrophosphate decarboxylase, an enzyme of the cholesterol synthesis pathway. This cDNA encodes a 400 amino acid protein (43 kDa) which resembles the coding sequence of an unidentified and incomplete open reading frame adjacent to the COQ2 gene of Saccharomyces cerevisiae. We also found an expression sequence tag clone made from human infant brain cDNA to be almost identical to our cDNA sequence.

REFERENCES:
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