DNA cancer vaccines

Details DNA cancer vaccines DNA cancer vaccines

2005-02-24

2009-10-20

Ton, Thaian N (Department: 1632)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

Reexamination Certificate

active

07605139

ABSTRACT:
A plurality of DNA cancer vaccines and their uses in treating cancer are disclosed. Genes encodingMycobacterium bovis bacillusCalmette-Guérin (M. bovisBCG) recombinant antigens and genes encoding interleukin-12 heterodimer were respectively cloned into eukaryotic expression vectors to express the encoded recombinant proteins in mammalian cells in vivo whereby specific immune responses are evoked and are effective in preventing, attenuating and/or suppressing the growth of a tumor.

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