DNA-based computer

Details DNA-based computer DNA-based computer

1996-02-07

1999-09-21

Jones, W. Gary

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435 6, 435 912, 364496, 364497, 364498, 364499, C12P 1934, C12Q 168, G06G 758

Patent

active

059553227

ABSTRACT:
The present invention relates to a DNA-based computer which is able to perm mathematical calculations such as addition as well as logical operations. It is based, at least in part, on the discovery that DNA molecules can be used to perform operations analogous to "bit-flipping" in computers. This capability, referred to herein as "molecular bit-flipping", derives from the complementary nature of DNA sequences. According to the present invention, input data are each represented by single-stranded DNA molecules. Complementary DNA sequences are incorporated such that input molecules, which bear a relationship defined by the operation, hybridize and permit one or more template DNA strands to serve as templates for primer extension. Primer extension, in turn, creates a result DNA molecule which represents the output data, and may be read using straightforward molecular biological techniques.

REFERENCES:
patent: 4683202 (1987-07-01), Mullis
Guarnieri et al. Science 273:220-223, Jul. 12, 1996.
Lipton, R. Science 268:542-545, Apr. 28, 1995
Adleman et al. Science 266:1021-1024, Nov. 11, 1994.
Zhang et al. Computer Applications in the Biosciences 10(3):309-317, 1994.

Affiliated with

Also associated with

Rating

DNA-based computer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA-based computer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA-based computer will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-79420