Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Reexamination Certificate
2005-01-11
2005-01-11
Barts, Samuel (Department: 1623)
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
C435S006120, C435S091510, C435S091100, C435S091200, C422S069000, C422S105000, C422S105000, C422S105000, C422S052000, C204S452000, C536S023100, C536S025300, C536S024300, C536S025320
Reexamination Certificate
active
06841128
ABSTRACT:
The present invention provides a DNA base sequencing system having a compact, simple and convenient structure.In one embodiment of the present invention, a reaction chamber module for pyrosequencing in which a multiple number of reaction vessels (reaction chambers)10and reagent-introducing narrow tubes6are integrated is formed in a device board5. Reagents held in reagent reservoirs1, 2, 3and4mounted separately from this reaction chamber module are introduced into the reaction vessels10via reagent-introducing narrow tubes (capillaries)6. The reagent-introducing narrow tubes (capillaries)6at the area of 2 cm from the reaction vessels10are structured with narrow capillaries having an inner diameter of about 0.1 mm and the conductance of these capillaries for the reagent solution determines the injection speed of the solution.Using the present invention, many kinds of DNAs can be analyzed simultaneously.
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Ronaghi et al. Science, (1998), vol. 281, pp. 363-365.*
Ronaghi et al., “A Sequencimg Method Based on Real-Time Pyrophosphate,” Science, vol. 281 (1998), p. 363-365.
Kambara Hideki
Miyahara Yuji
Zhou Guohua
A. Marquez, Esq. Juan Carlos
Barts Samuel
Fisher Esq. Stanley P.
Hitachi , Ltd.
Lewis Patrick T.
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