Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-08-12
1999-08-10
Elliott, George C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 2431, C07H 2104, C12N 1512
Patent
active
059360780
ABSTRACT:
The present invention relates to a DNA selected from DNAs, each having the nucleotide sequence of one of Sequence Nos. 1 to 17, complementary to the RNA strand of mRNA with the varied expression level in patients with Alzheimer's disease, compared with the expression level of the mRNA in normal human brain or a DNA hybridizable with the above-mentioned DNA wherein one or more nucleotides in said DNA are deleted or substituted with other nucleotides or one or more nucleotides are added to said DNA, a polypeptide encoded by the DNA, an antibody recognizing the polypeptide, and the diagnosis, therapeutic treatment and research works of patients with Alzheimer's disease, using the DNA, the polypeptide and the antibody.
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Hashida Hideji
Kuga Tetsuro
Nakagawa Satoshi
Sakaki Yoshiyuki
Zhao Nanding
Elliott George C.
Kyowa Hakko Kogyo Co. Ltd.
Schwartzman Robert
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