DNA and expression vector encoding I.kappa.B Protein

Details DNA and expression vector encoding I.kappa.B Protein DNA and expression vector encoding I.kappa.B Protein

1995-06-06

1998-11-03

McKelvey, Terry A.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

435243, 4353201, 435410, 536 235, C12N 510, C12N 100, C12N 1512, C12N 1563

Patent

active

058307567

ABSTRACT:
Compositions and methods of using the same are described that have applications for the identification of prophylactics or therapeutics for the treatment of diseases resulting from altered gene expression, including genes that encode cytokines or related molecules.

REFERENCES:
patent: 4399216 (1983-08-01), Axel et al.
patent: 4419446 (1983-12-01), Howley et al.
patent: 4601978 (1986-07-01), Karin
patent: 4656134 (1987-04-01), Ringold
patent: 4666848 (1987-05-01), Gelfand et al.
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis
patent: 4711845 (1987-12-01), Gelfand et al.
patent: 4800159 (1989-01-01), Mullis et al.
patent: 4803164 (1989-02-01), Hitzeman et al.
patent: 4990337 (1991-02-01), Kurihara et al.
patent: 5183736 (1993-02-01), Pfahl et al.
patent: 5385915 (1995-01-01), Buxbaum et al.
Ngo et al, The Protein Folding Problem and Tertiary Structure Prediction, Mertz et al (eds.), 1994, Birkhouser, Boston, MA, pp. 433 and 492-495.
Anderson, W.F., "Prospects for Human Gene Therapy", Science, 226:401-409 (1984).
Aviv et al., "Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose", Proc. Natl. Acad. Sci. (USA), 69:1408-1412 (1972).
Baeuerle et al., "of Activation of DNA-Binding Activity in an Apparently Cytoplasmic Precursor of the NF-.kappa.B Transcription Factor", Cell, 53:211-217 (1988).
Baererle et al., "I.kappa.B: A Specific Inhibitor of the NF-.kappa.B Transcription Factor", Science, 242:540-546 (1988).
Baererle et al., "Activation of NF-.kappa.B: A Transcription Factor Controlling Expression of the Immunoglobulin .kappa.Light-chain Gene and of HIV", in The Control of Human Retrovirus Gene Expression, pp. 217-226, Franza et al. eds., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1988).
Baeuerle et al., "A 65-.kappa.D subunit of active NF-.kappa.B is required for inhibition of NF-.kappa.B by I.kappa.B", Genes and Development, 3: 1689-1698 (1989).
Baldwin, A.S., "Analysis of Sequence-Specific DNA-Binding Proteins by the Gel Mobility Shift Assay", DNA & Protein Engineering Techniques, 2:73-76 (1990).
Baldwin et al., "Two transcription factors, NF-.kappa.B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter", Proc. Natl. Acad. Sci. (USA), 85:723-727 (1988).
Baldwin et al., "Binding of a Nuclear Factor to a Regulatory Sequence in the Promoter of the Mouse H-2K.sup.b Class I Major Histocompatibility Gene", Mol. Cell. Biol. 7:305-313 (1987).
Balkwill et al., "The cytokine network", Immunol. Today, 10:299-303 (1989).
Bolivar et al., "Construction and Characterization of New cloning Vehicles: II. A Multipurpose Cloning System", Gene, 2:95-113 (1977).
Boyum, A., "Isolation of Mononuclear Cells and Granulocytes from Human Blood", Scandinavian J. of Clinical Lab. Invest., 21:77-89 (1968).
Brini et al., "Cyclosporin A inhibits induction of IL-2 receptor .alpha.chain expression by affecting activation of NF-.kappa.B-like factor(s) in cultured human T lymphocytes", Eur. Cytokine Net., 1:131-139 (1990).
Broach et al., "Transformation in Yeast: Development of a Hybrid Cloning Vector and isolation of the CAN1 Gene", Gene, 8:121-133 (1979).
Broach, J.R., "Construction of High Copy Yeast Vectors Using 2-82 m Circle Sequences", Meth. Enzymol., 101:307-325 (1983).
Caput et al., "Identification of a common nucleotide sequence in the 3'-untranslated region mRNA molecules specifying imflammatory mediators", Proc. Natl. Acad. Sci. (USA), 83:1670-1674 (1986).
Carthew et al., "An RNA Polymearse II Transcription Factor Binds to an Upstream Element in The Adenovirus Major Late Promoter", Cell, 43:439-448 (1985).
Chirgwin et al., "Isolation of Biologically Active Ribonucleic Acid from Sources Enriched in Ribonuclease", Biochemistry, 18:5294-5299 (1979).
Clarke et al., "Selection Procedure for Isolation of Centromere DNAs fromSaccharomyces cerevisiae", Meth. Enzymol., 101:300-307 (1983).
Clewell et al., "Supercoiled Circular DNA-Protein Complex in Escherichia coli: Purification and Induced Conversion to an Open Circular DNA Form", Proc. Natl. Acad. Sci. (USA), 62:1159-1166 (1969).
Clewell, D.B., "Nature of Col E.sub.1 Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol", J. Bacteriol., 110:667-676 (1972).
Cohen et al., "Nonchromosomal Antibiotic Resitance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA", Proc. Natl. Acad. Sci. (USA), 69:2110-2114 (1972).
Depicker et al., "Nopaline Synthase: Transcript Mapping and DNA Sequence", J. Mol. Appl. Genet., 1:561-573 (1982).
Eierman et al., "Human Monocyte Inflammatory Mediator Gene Expression is Selectively Regulated by Adherence Substrates", J. Immunol., 142:1970-1976 (1989).
Fiers et al., "Complete nucleotide sequence of SV40 DNA", Nature, 273:113-120 (1978).
Folks et al., "Tumor necrosis factor .alpha.induces expression of human immunodeficiency virus in a chronically infected T-cell clone", Proc. Natl. Acad. Sci. (USA), 86:2365-2368 (1989).
Ghosh et al., "Activation in vitro of NF-.kappa.B by phosphorylation of its inhibitor I.kappa.B", Nature, 344:678-682 (1990).
Goeddel et al., "Synthesis of human fibroblast interferon by E. coli", Nucl. Acids. Res., 8:4057-4074 (1980).
Graham et al., "A New Technique for the Assay of Infectivity of Human Adenovirus 5 DNA", Virology, 52:456-467 (1973).
Greene, A. E., "Human Biopsy Material from Genetic Abnormalities", in Tissue Culture: Methods and Applications, pp. 69-72, Kruse et al. eds., Academic Press, New York, NY (1973).
Hack et al., "Increased Plasma Levels of Interleukin-6 in Sepsis", Blood, 74:1704-1710 (1989).
Hanahan, D., "Studies on Transformation of Escherichia coli with Plasmids", J. Mol. Biol., 166:557-580 (1983).
Haskill et al., "Adherence Induces Selective mRNA Expression of Monocyte Mediators and Proto-Oncogenes", J. Immunol., 140:1690-1694 (1988).
Hitzeman et al., "Isolation and Charcterization of the Yeast 3-Phosphoglycerokinase Gene (PGK) by and Immunological Screening Technique", J. Biol. Chem., 255:12073-12080 (1980).
Holland et al., "Isolation and Identification of Yeast Messenger Ribonucleic Acids Coding for Enolase, Glyceraldehyde-3-phosphate Dehydrogenase, and Phosphoglycerate Kinase", Biochemistry, l 17:4900-4907 (1978).
Holland et al., "The Primary Structures of Two Yeast Enolase Genes: Homology Between The 5' Noncoding Flanking Regions Of Yeast Enolase And Givceraldehyde Dehydrogenase Genes", J. Biol. Chem., 256:1385-1395 (1981).
Hsiao et al., "High-frequency transformation of yeast by plasmids containing the cloned yeast ARG4 gene", Proc. Natl. Acad. Sci. (USA), 76:3829-3833 (1979).
Huynh et al., "Constructing and Screening cDNA Libraries in .lambda.gt10 and .lambda.gt11", in DNA Cloning: A Practical Approach, vol. 1, pp. 49-78, Glover ed., IRL Press, Oxford, UK (1985).
Ish-Horowicz et al., "Rapid and efficient cosmid cloning", Nucl. Acids Res., 9:2989-2998 (1981).
Kadonaga et al., "Affinity purification of sequence-specific DNA binding proteins", Proc. Natl. Acad. Sci. (USA), 83:5889-5893 (1986).
Kaighn, M.E., "Human Liver Cells", in Tissue Culture: Methods and Applications 54-58, Kruse et al. eds., Academic Press, New York, NY (1973).
Kasten, F.H., "Mammalian Myocardial Cells", in Tissue Culture: Methods and Applications pp. 72-81, Kruse et al. eds., Academic Press, New York, NY (1973).
Kawasaki et al., "Detection of Gene Expression ", in PCR Technology: Principles and Applications for DNA Amplification pp. 89-97, Erlich et al., Stockton, NY (1989).
Kieran et al., "The DNA Binding Subunit of NF-.kappa.B Is Identical to Factor KBF1 and Homologous to the rel Oncogene Product", Cell, 1007-1018 (1990).
Laemmli, U.K., "Cleavage of Structural Proteins during the Assembly of the Head Bacteriophage T4", Nature, 227:680-685 (1970).
Lenardo et al., "NF-.kappa.B: A Pleiotropic Mediator of Inducible and Tissue-Specific Gene Control", Cell, 58:227-229 (1989).
Lux et al., "Analysis of cDNA for human erythrocyte ankyrin indicates a repeated structure with homology to tissue differentiation and cell

Affiliated with

Also associated with

Rating

DNA and expression vector encoding I.kappa.B Protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with DNA and expression vector encoding I.kappa.B Protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and DNA and expression vector encoding I.kappa.B Protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-688520