DNA and amino acid sequence of a tyrosine ammonia lyase...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S232000, C435S320100, C536S023200

Reexamination Certificate

active

07067302

ABSTRACT:
A novel tyrosine ammonia lyase enzyme was identified in the bacteriumRhodobacter sphaeroides. This enzyme has a higher activity for tyrosine than for phenylalanine and is useful for the production of para-hydroxycinnamic acid directly from tyrosine. The gene encoding this enzyme was cloned by direct amplification using the genomic DNA and was expressed inE. coli.

REFERENCES:
patent: 2003/0233675 (2003-12-01), Cao et al.
Accession No. ADN25163), is 91.6% identical to Applicants polypeptide of SEQ ID No.: 3, see the encllosed sequence search alignment.

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