Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1978-07-10
1979-12-11
Killos, Paul J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
562463, C07C17700
Patent
active
041784570
ABSTRACT:
Novel 16-phenoxy and 16-(o, m or p)-substituted phenoxy derivatives of (dl)-9-keto-11.alpha.,15.alpha.-dihydroxy-17,18,19,20-tetranorprosta-4,5,1 3-trans-trienoic acid, the pharmaceutically acceptable, non-toxic lower alkyl esters and salts thereof and processes for the production of such compounds. These compounds possess prostaglandin-like activities and thus are useful in the treatment of mammals where prostaglandins are indicated. They are particularly useful as inhibitors of gastric acid secretion; and as agents for the control of asthmatic attack, because of their bronchodilating activity.
REFERENCES:
patent: 3985791 (1976-10-01), Fried
Edwards John A.
Garay Gabriel
Van Horn Albert R.
Blaufarb Gerard A.
Killos Paul J.
Krubiner Alan M.
Syntex (U.S.A.) Inc.
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