(dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoi

Details (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoi (dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoi

1978-07-10

1979-12-11

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562463, C07C17700

Patent

active

041784570

ABSTRACT:
Novel 16-phenoxy and 16-(o, m or p)-substituted phenoxy derivatives of (dl)-9-keto-11.alpha.,15.alpha.-dihydroxy-17,18,19,20-tetranorprosta-4,5,1 3-trans-trienoic acid, the pharmaceutically acceptable, non-toxic lower alkyl esters and salts thereof and processes for the production of such compounds. These compounds possess prostaglandin-like activities and thus are useful in the treatment of mammals where prostaglandins are indicated. They are particularly useful as inhibitors of gastric acid secretion; and as agents for the control of asthmatic attack, because of their bronchodilating activity.

REFERENCES:
patent: 3985791 (1976-10-01), Fried

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