Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds antigen or epitope whose amino acid sequence is...
Patent
1999-10-04
2000-05-09
Patterson, Jr., Charles L.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds antigen or epitope whose amino acid sequence is...
435 6, 435 71, 514 12, 530350, 5303879, A61K 3816, A61K 3940, C12Q 168, C07K 1400, C07K 1612
Patent
active
060600551
ABSTRACT:
The invention provides Div1b polypeptides and DNA (RNA) encoding Div1b polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Div1b polypeptides to screen for antibacterial compounds.
REFERENCES:
Yi Q, et al., GenBank Submission, Accession No.P06136, "Cell Division Protein FTSQ.".
Guzman, et al., "Domain-Swapping Analysis of FtsI, FtsL, and FtsQ, Bitopic Membrane Protein Essential for Cell Division in Escherichia coli." Journal of Bacteriology, vol. 194, No. 16, pp. 5094-51038, Aug. (1997).
Dai, et al., "Topological Characterization of the Essential Escherichia coli Cell Division Protein FtsN." Journal of Bacteriology, vol. 178, No. 5, pp. 1328-1334, Mar. (1996).
Carson, et al., "The FtsQ Protein of Escherichia coli: membrane Topology, Abundance, and cell Division Phenotypes Due to Overproduction and Insertion Mutation." Journal of Bacteriology, vol. 173, No. 7, pp. 2187-2195, Apr. (1991).
Hodgson John Edward
Payne David John
Pearce, Jr. Kenneth H.
Pearson Stewart Campbell
Deibert Thomas S.
Gimmi Edward R.
King William T.
Patterson Jr. Charles L.
SmithKline Beecham Corporation
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