Diuretic compositions and methods of producing diuresis

Details Diuretic compositions and methods of producing diuresis Diuretic compositions and methods of producing diuresis

1986-04-16

1988-01-12

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 10, A61K 3734

Patent

active

047191996

ABSTRACT:
2- or 3-.beta.-Indolylalanyl and .beta.-indolylglycyl vasopressins are prepared by standard peptide synthetic methods. These 2- or 3-TRP vasopressins have vasopressin antagonist activity.

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patent: 4597901 (1986-07-01), Yim
Stedman's Medical Dictionary, 23rd Ed., The Williams and Wilkins Co., Baltimore, 1976, p. 416.
Morrison and Boyd, Organic Chemistry, Allyn and Bacon, p. 1135 (1975).
M. Manning et al., Nature, 308 652 (1984).
M. Lebl et al., Proceedings of the 17th European Peptide Symposium, 1982.
Textbook of Biochemistry, 4th Ed., The Macmillan Co. N.Y., 1966, pp. 1475-1476.
Chemical Abstracts, vol. 83, 67 (1975) (Abstract No. 172906e).
Chemical Abstracts, vol. 85, 67 (1976) (Abstract No. 57024v).
Schroder and Lubke, The Peptides, vol. II Academic Press, N.Y. 1966, pp. 366-373.
W. Rittel et al., Experientia, 32(2), 246-248 (976).

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