Diuretic and vasodilating tricyclic quinazolines

Details Diuretic and vasodilating tricyclic quinazolines Diuretic and vasodilating tricyclic quinazolines

1978-09-05

1980-10-14

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544250, A61K 31505, C07D48714

Patent

active

042281679

ABSTRACT:
Novel imidazo[2,1-b]quinazolines and pyrimido-[2,1-b]quinozolines represented by the formula, ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and A are as defined in the specification were prepared. They have prominent pharmacological properties such as diuretic and vasodilating activity.

REFERENCES:
patent: 3932407 (1976-01-01), Beverung, Jr. et al.
patent: 3957819 (1976-05-01), White
patent: 3976645 (1976-08-01), White
patent: 3984556 (1976-10-01), Hardtmann
patent: 4126683 (1978-11-01), White et al.
Zderic, et al., Chemical Abstracts, vol. 55, 8472e (1960).
Migrdichian, Organic Synthesis, vol. 1, p. 580, Reinhold Publishing Corp., New York (1957).
Fuson, Reactions of Organic Compounds, John Wiley & Sons, New York, pp. 648-652 (1964).

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